Thymonucleic Acid in Tumors**
نویسنده
چکیده
THE ROLE OF THYMONUCLEIC ACID IN NORMAL CELLS Chromosomes and Genes Cytoplasmic Nucleic Acids Protein Synthesis Bacteria and Filterable Viruses THE ROLE OF THYMONUCLEIC ACID IN NEOPLASTIC CELLS The Significance of Nucleic Acids in the Somatic Mutation Theory of Etiology Chemical Evidence of Disturbance of Nucleic Acids in Tumors Histochemical and Cytochemical Evidence of Disturbance of Thymonucleic Acid in Tumors Cytological Evidence of Abnormalities of Nucleic Acids in Chromosomes and Nucleoli in Tumors Nucleoproteins in Tumor-Inciting Agents
منابع مشابه
The Structure of Thymonucleic Acid
The earlier work on thymonucleic acid by Levene and Mandell and by Levene and Jacobs2 led to the isolation of monophosphoric esters of pyrimidine nucleosides and diphosphoric esters of pyrimidine nucleosides. These observations were corroborated by Thannhauser and coworkers.3 In a recent publication Levene and London4 reported the isolation of a guanine nucleoside and the present paper contains...
متن کاملExploratory experimentation and the role of histochemical techniques in the work of Jean Brachet, 1938-1952.
[There are serious limitations on the available histochemical, biochemical, and physical methods for estimating precise quantities and locations of nucleic acids.] Reliable results can therefore only be obtained if all available tests are applied and give concordant results; it is also imperative, whenever possible, to check cytochemical results with microchemical estimations of pentoseand thym...
متن کاملThe Chromatographic Separation of Phosphatases in Snake Venoms*
This report describes a method of preparing samples of phosphodiesterase suitable for some chemical studies of desoxyribonucleic acid. A study of the use of purified phosphodiesterase in hydrolyzing thymonucleic acid has already been made (1). The source of our phosphodiesterase (snake venoms) was suggested by the work of Gulland and Jackson (2), although it now seems to us that their conclusio...
متن کاملThe Chromatographic Separation of Phosphatases in Snake Venoms*
This report describes a method of preparing samples of phosphodiesterase suitable for some chemical studies of desoxyribonucleic acid. A study of the use of purified phosphodiesterase in hydrolyzing thymonucleic acid has already been made (1). The source of our phosphodiesterase (snake venoms) was suggested by the work of Gulland and Jackson (2), although it now seems to us that their conclusio...
متن کاملThe enzymatic degradation of thymonucleic acid. I. The preparation of oligonucleotides.
This study constitutes the first phase of an investigation undertaken to develop a method for obtaining mononucleotides from the desoxyribonucleic acid of calf thymus, and concerns itself with the first step in the procedure, namely the production of oligonucleotides. Fischer, LehmannEchternacht, and Boettger (1) have studied the degradation of thymonucleic acid, prepared by Levene’s (2) method...
متن کامل